David C.S. Huang

Statistics

Publications

208

Citations

41.2K

H-Index

Active since

1991

Affiliations

Walter and Eliza Hall Institute of Medical Research(Current)

The University of Melbourne

The Royal Melbourne Hospital

Peter MacCallum Cancer Centre

Monash University

David C.S. Huang is an author at Walter and Eliza Hall Institute of Medical Research specializing in apoptosis, bcl-2 family proteins, and life sciences.

ORCID

Publications per year

1991–2025

208

Publications

208

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Andrew J. Souers, Joel D. Leverson, Erwin R. Boghaert et al. · Nature Medicine · 2013 · 3K citations

Medicine, Oncology, Pharmacology +10

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Lin Chen, Simon N. Willis, Andrew H. Wei et al. · Molecular Cell · 2005 · 1.8K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

Philippe Bouillet, Donald Metcalf, David C.S. Huang et al. · Science · 1999 · 1.5K citations

Life Sciences, Cell Biology, Immunology +17

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Mark F. van Delft, Andrew H. Wei, Kylie D. Mason et al. · Cancer Cell · 2006 · 1.2K citations · Full text

Life Sciences, Cell Biology, Pharmacology +10

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x <sub>L</sub> , but not Bcl-2, until displaced by BH3-only proteins

Simon N. Willis, Grant Dewson, Andrew H. Wei et al. · Genes & Development · 2005 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

1–5 of 208