Philippe Bouillet

Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

Philippe Bouillet, Donald Metcalf, David C.S. Huang et al. · Science · 1999 · 1.5K citations

Clinical Immunology, Certain Apoptotic Responses, Preclude Autoimmunity +18

ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

Hamsa Puthalakath, Lorraine A. O’Reilly, Priscilla Gunn et al. · Cell · 2007 · 1.4K citations · Full text

Bh3-only Protein Bim, Apoptosis, Cell Death +4

Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak

Simon N. Willis, Jamie I. Fletcher, Thomas Kaufmann et al. · Science · 2007 · 1.1K citations

Pro-survival Bcl-2-like Relatives, Signal Transduction, Bh3-only Members +11

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

Philippe Bouillet, Jared F. Purton, Dale I. Godfrey et al. · Nature · 2002 · 764 citations

Hematological Malignancy, Autoimmune Disease, Lymphocyte Development +9

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

Vanessa S. Marsden, Liam O’Connor, Lorraine A. O’Reilly et al. · Nature · 2002 · 560 citations

Mitophagy, Bcl-2-regulated Caspase Activation, Signal Transduction +9