Concepedia

Proteasome Inhibitors Enhance Gene Delivery by AAV Virus Vectors Expressing Large Genomes in Hemophilia Mouse and Dog Models: A Strategy for Broad Clinical Application

Paul E. Monahan, Clinton D. Lothrop, Junjiang Sun, Matthew L. Hirsch, Tal Kafri, Boris Kantor, Rita Sarkar, D. Michael Tillson, Joseph R Elia, R. Jude Samulski

Molecular Therapy · 2010 · 119 citations · 46 references

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46

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

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Effect of Genome Size on AAV Vector Packaging

Zhijian Wu, Hongyan Yang, Peter Colosi · Molecular Therapy · 2009 · 972 citations · Full text

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Quantitative Analysis of the Packaging Capacity of Recombinant Adeno-Associated Virus

Jian-Yun Dong, Peidong Fan, Raymond A. Frizzell · Human Gene Therapy · 1996 · 577 citations

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Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

Zhong Li, Baozheng Li, Cathryn Mah et al. · Proceedings of the National Academy of Sciences · 2008 · 549 citations · Full text

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Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in <i>mdx</i> mouse model

Bing Wang, Juan Li, Xiao Xiao · Proceedings of the National Academy of Sciences · 2000 · 497 citations

, , +17