Concepedia

Investigation of the pharmacokinetics and determination of tramadol in rabbit plasma by a high-performance liquid chromatography–diode array detector method using liquid–liquid extraction

Aysel Küçük, Yücel Kadıoğlu, Fikret Çelebi

Journal of Chromatography B · 2004 · 50 citations · 18 references

DOI

Concepts

References

18

Applied Biopharmaceutics and Pharmacokinetics.

Annals of Internal Medicine · 1981 · 1.2K citations

, , +17

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

Robert B. Raffa, Elmar Friderichs, Wolfgang Reimann et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 1.2K citations

, , +17

Kinetic spectrophotometric determination of tramadol hydrochloride in pharmaceutical formulation

Hisham Ezzat Abdellatef · Journal of Pharmaceutical and Biomedical Analysis · 2002 · 90 citations

, , +13

Method development and validation of a high-performance liquid chromatographic method for tramadol in human plasma using liquid–liquid extraction

Siew Hua Gan, Rusli Ismail, W. A. Wan Adnan et al. · Journal of Chromatography B · 2002 · 88 citations

, , +15

Validation of a high-performance liquid chromatography method for tramadol and o-desmethyltramadol in human plasma using solid-phase extraction

Siew Hua Gan, Rusli Ismail · Journal of Chromatography B Biomedical Sciences and Applications · 2001 · 84 citations

, , +15