Robert B. Raffa

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

Robert B. Raffa, Elmar Friderichs, Wolfgang Reimann et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 1.2K citations

Medicine, Pharmacology, Pharmacotherapy +17

Topiramate: Preclinical Evaluation of a Structurally Novel Anticonvulsant

Richard P. Shank, Joseph F. Gardocki, Jeffry L. Vaught et al. · Epilepsia · 1994 · 346 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Testing for synergism over a range of fixed ratio drug combinations: Replacing the isobologram

Ronald J. Tallarida, Robert B. Raffa · Life Sciences · 1995 · 116 citations

Medicine, Pharmacology, Pharmacodynamics +4

Loss of antiallodynic and antinociceptive spinal/supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum

Di Bian, Michael H. Ossipov, Mohab Ibrahim et al. · Brain Research · 1999 · 89 citations

Nursing, Neuroscience, Pharmacology +14

Cocaine withdrawal in Planaria

Robert B. Raffa, Joseph M. Valdez · European Journal of Pharmacology · 2001 · 74 citations

Nursing, Pharmacology, Addiction Psychiatry +6