Richard P. Shank

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

Robert B. Raffa, Elmar Friderichs, Wolfgang Reimann et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 1.2K citations

Medicine, Pharmacology, Pharmacotherapy +17

An Overview of the Preclinical Aspects of Topiramate: Pharmacology, Pharmacokinetics, and Mechanism of Action

Richard P. Shank, Joseph F. Gardocki, Anthony J. Streeter et al. · Epilepsia · 2000 · 814 citations

Medicine, Neuroscience, Pharmacology +17

β-Amyloid1–42 Binds to α7 Nicotinic Acetylcholine Receptor with High Affinity

Hoau-Yan Wang, Daniel H. S. Lee, Michael R. D’Andrea et al. · Journal of Biological Chemistry · 2000 · 805 citations · Full text

Life Sciences, Biochemistry, Neuroscience +10

Pyruvate car☐ylase: an astrocyte-specific enzyme implicated in the replenishment of amino acid neurotransmitter pools

Richard P. Shank, Gudrun S. Bennett, Svend O. Freytag et al. · Brain Research · 1985 · 469 citations

Life Sciences, Biochemistry, Neuroscience +16

Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol.

Robert B. Raffa, Elmar Friderichs, Wolfgang Reimann et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 440 citations

Medicine, Medicinal Chemistry, Pharmacology +17