Concepedia

Method development and validation of a high-performance liquid chromatographic method for tramadol in human plasma using liquid–liquid extraction

Siew Hua Gan, Rusli Ismail, W. A. Wan Adnan, Zutian Wan

Journal of Chromatography B · 2002 · 88 citations · 8 references

Concepts

PharmacyPharmaceutical AnalysisPharmacologyChromatographic AnalysisClinical PharmacologyAnalytical ChromatographyChromatographic Analysis Of PharmaceuticalsChromatographic Method ValidationChromatographyLiquid ChromatographyLiquid-liquid ExtractionAnalytical Liquid ChromatographyAnalytical Method DevelopmentHigh-performance Liquid ChromatographyHigh-performance Liquid Chromatography ColumnsHigh-performance Liquid Chromatography Method DevelopmentLiquid Chromatography-mass SpectrometryPlasma Sampling

References

8

Practical HPLC Method Development

Analytical Chemistry · 1993 · 1.4K citations

Business, Pharmaceutical Analysis, Norm-referenced Assessment +5

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

Robert B. Raffa, Elmar Friderichs, Wolfgang Reimann et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 1.2K citations

Medicine, Pharmacology, Pharmacotherapy +17

Practical HPLC Method Development

Leonie Krull · TrAC Trends in Analytical Chemistry · 1989 · 226 citations

Business, Pharmaceutical Analysis, Norm-referenced Assessment +5

The analysis of drugs in biological fluids

Choice Reviews Online · 1996 · 101 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +17

Validation of a high-performance liquid chromatography method for tramadol and o-desmethyltramadol in human plasma using solid-phase extraction

Siew Hua Gan, Rusli Ismail · Journal of Chromatography B Biomedical Sciences and Applications · 2001 · 84 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +15