Applied Biopharmaceutics and Pharmacokinetics.

Abstract

Mathematical fundamentals on pharmacokinetics introduction to biopharmaceutics and pharmacokinetics one compartment model physiological factors relating to drug absorption biopharmaceutic considerations in drug product design modified release drug products delivery of biotechnical products and targetted drug delivery systems pharmacokinetics of drug absorption bioavailability and bioequivalence multicompartmental models drug distribution and protein binding drug clearance drug metabolism and hepatic clearance pharmacokinetics after intravenous infusion pharmacokinetics after multiple dosing non-linear pharmacokinetics introduction to clinical pharmacokinetics application of pharmacokinetics to clinical situations relationship between pharmacokinetic parameters and pharmacologic response physiologic pharmacokinetic model and statistical moment computer applications in pharmacokinetics biopharmaceutics and pharmacokinetic studies in drug development appendix.