Concepedia

Physiological Compartment Models

Physiological Compartment Model is a type of mathematical model in pharmacokinetics and systems biology that partitions the body or a biological system into interconnected compartments, each representing a physiologically distinct tissue or organ with realistic anatomical and physiological parameters, to accurately simulate the distribution and elimination of substances based on known physiological structures and blood flow rates.

79

Publications

6.9K

Citations

241

Authors

131

Institutions

Publications per year

2017–2026

8

Variants

Pbpk ModelsPhysiologically Based Pharmacokinetic Models

Parents

Publications

79

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Generalizations

Clifford S. Patlak, Ronald G. Blasberg · Journal of Cerebral Blood Flow & Metabolism · 1985 · 1.7K citations · Full text

, , +17

Applied Biopharmaceutics and Pharmacokinetics.

Annals of Internal Medicine · 1981 · 1.2K citations

, , +17

BioAmbients: an abstraction for biological compartments

Aviv Regev, Ekaterina M. Panina, William B. Silverman et al. · Theoretical Computer Science · 2004 · 476 citations

, , +6

Toxicokinetics in aquatic systems: Model comparisons and use in hazard assessment

Peter F. Landrum, Michael J. Lydy, Henry Lee · Environmental Toxicology and Chemistry · 1992 · 349 citations · Full text

, , +10

Uncertainty in the analysis of tracer kinetics using dynamic contrast‐enhanced <i>T</i><sub>1</sub>‐weighted MRI

David L. Buckley · Magnetic Resonance in Medicine · 2002 · 266 citations

, , +17

1–5 of 79

Authors

241

  1. ED
    E.V.R. Di Bella

    University of Utah, United States

    2 publications · 81 citations

    2

    h-index

  2. HL
    Henry Lee

    Stanford University, United States

    2 publications · 365 citations

    2

    h-index

  3. MJ
    Michael J. Lydy

    Southern Illinois University Carbondale, United States

    2 publications · 365 citations

    2

    h-index

  4. MP
    Maria Pia Saccomani

    University of Padua, Italy

    2 publications · 46 citations

    2

    h-index

  5. RF
    Raymond F. Muzic

    Case Western Reserve University, United States

    2 publications · 145 citations

    2

    h-index

1–5 of 241

Institutions

131

  1. University of Padua

    Padua, Italy

    4 h-index

    6 publications

    259 citations

  2. University of Minnesota

    Minneapolis, United States

    2 h-index

    2 publications

    45 citations

  3. Washington University in St. Louis

    St Louis, United States

    2 h-index

    2 publications

    40 citations

  4. Case Western Reserve University

    Cleveland, United States

    2 h-index

    3 publications

    165 citations

  5. National Institutes of Health Clinical Center

    Bethesda, United States

    2 h-index

    4 publications

    1.8K citations

  6. Environmental Protection Agency

    Washington, United States

    2 h-index

    3 publications

    439 citations

  7. Royal Adelaide Hospital

    Adelaide, Australia

    2 h-index

    3 publications

    343 citations

  8. Stanford University

    Stanford, United States

    2 h-index

    4 publications

    147 citations

1–8 of 131

Venues

  1. PubMed

    Repository · 4 publications · 182 citations

    4

    h-index

  2. Journal of Applied Physiology

    3 publications · 194 citations

    3

    h-index

  3. Health Physics

    3 publications · 66 citations

    3

    h-index

  4. IEEE Transactions on Biomedical Engineering

    3 publications · 145 citations

    3

    h-index

  5. 2

    h-index

1–5