Concepedia

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

Daniel Zwilling, Shaoyi Huang, Korrapati V. Sathyasaikumar, Francesca M. Notarangelo, Paolo Guidetti, Hui‐Qiu Wu, Jason H. Lee, Jennifer K. Truong, Yaisa Andrews‐Zwilling, Eric Hsieh,

Cell · 2011 · 514 citations · 55 references

DOIFull text

Open access

Concepts

References

55

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

, , +17

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

, , +16

High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience · 2000 · 1.9K citations · Full text

, , +17

Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo

Eberhard Scherzinger, Rudi Lurz, Mark Turmaine et al. · Cell · 1997 · 1.3K citations · Full text

, , +10

Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

Robert Schwarcz, William O. Whetsell, Richard M. Mangano · Science · 1983 · 1.3K citations

, , +16