Rudi Lurz

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

Dagmar E. Ehrnhoefer, Jan Bieschke, Annett Boeddrich et al. · Nature Structural & Molecular Biology · 2008 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +14

Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo

Eberhard Scherzinger, Rudi Lurz, Mark Turmaine et al. · Cell · 1997 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +10

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington’s disease pathology

Eberhard Scherzinger, Annie Sittler, Katja Schweiger et al. · Proceedings of the National Academy of Sciences · 1999 · 729 citations

Life Sciences, Biochemistry, Molecular Biology +17

Accumulation of Mutant Huntingtin Fragments in Aggresome-like Inclusion Bodies as a Result of Insufficient Protein Degradation

Stephanie Waelter, Annett Boeddrich, Rudi Lurz et al. · Molecular Biology of the Cell · 2001 · 632 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells

Alessandro Prigione, Beatrix Fauler, Rudi Lurz et al. · Stem Cells · 2010 · 607 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17