Concepedia

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

Dagmar E. Ehrnhoefer, Jan Bieschke, Annett Boeddrich, Martin Herbst, Laura Masino, Rudi Lurz, Sabine Engemann, Annalisa Pastore, Erich E. Wanker

Nature Structural & Molecular Biology · 2008 · 1.4K citations · 35 references

DOI

Concepts

References

35

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

, , +17

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

Monica Bucciantini, Elisa Giannoni, Fabrizio Chiti et al. · Nature · 2002 · 2.4K citations

, , +17

NACP, A Protein Implicated in Alzheimer's Disease and Learning, Is Natively Unfolded

Paul H. Weinreb, Weiguo Zhen, Anna W. Poon et al. · Biochemistry · 1996 · 1.5K citations

, , +17

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

Harry LeVine · Methods in enzymology on CD-ROM/Methods in enzymology · 1999 · 1.4K citations

, , +12

The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

Akihiko Iwai, Eliezer Masliah, Makoto Yoshimoto et al. · Neuron · 1995 · 1.3K citations

, , +17