Sabine Engemann

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

Dagmar E. Ehrnhoefer, Jan Bieschke, Annett Boeddrich et al. · Nature Structural & Molecular Biology · 2008 · 1.4K citations

Off-pathway Oligomers, Protein Assembly, G Protein-coupled Receptor +5

Active demethylation of the paternal genome in the mouse zygote

Joachim Oswald, Sabine Engemann, Natasha Lane et al. · Current Biology · 2000 · 959 citations

Developmental Biology, Epigenetic Change, Genetics +11

Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

Dagmar E. Ehrnhoefer, Martin L. Duennwald, Phoebe Markovic et al. · Human Molecular Genetics · 2006 · 413 citations · Full text

Hd Flies, Green Tea Polyphenol, Genetics +18

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration <i>in vivo</i>

Xiaoqian Zhang, Donna L. Smith, Anatoli B. Meriin et al. · Proceedings of the National Academy of Sciences · 2005 · 243 citations · Full text

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

Volker Heiser, Sabine Engemann, W. Bröcker et al. · Proceedings of the National Academy of Sciences · 2002 · 206 citations · Full text