Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo
Cell · 1997 · 1.3K citations · 36 references
Neurodegenerative DiseasesMolecular NeuroscienceBiochemistryDegenerative PathologyNeurochemical BiomarkersProtein MisfoldingMedicineCell BiologyNeuropeptides
36
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.
Harry Towbin, T. Staehelin, J. Gordon · Proceedings of the National Academy of Sciences · 1979
Immunocytochemical TechniqueGlycobiologyPolyacrylamide Gels+19
53.8K citations
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
Marcy E. MacDonald · Cell · 1993
8.3K citations
Donald B. Smith, Kevin S. Johnson · Gene · 1988
6K citations
Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice
Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996
Knockout MouseNeurodegenerative DiseasesDevelopmental Biology+9
3.1K citations
Neuropathological Classification of Huntingtonʼs Disease
Jean‐Paul Vonsattel, Richard H. Myers, Thomas J. Stevens et al. · Journal of Neuropathology & Experimental Neurology · 1985
2.6K citations