Impaired Assembly yet Normal Trafficking of MHC Class I Molecules in Tapasin Mutant Mice

T cell receptor antagonist peptides induce positive selection

Kristin A. Hogquist, Stephen C. Jameson, William R. Heath et al. · Cell · 1994 · 2.8K citations

T-regulatory Cell, Immunology, Positive Selection +7

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes

Ulrich S. Schubert, Luis C. Antón, James S. Gibbs et al. · Nature · 2000 · 1.5K citations

Protein Chemistry, Biochemistry, Protein Folding +10

Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

Emmanuel J. H. J. Wiertz, Domenico Tortorella, Matthew Bogyo et al. · Nature · 1996 · 1.1K citations

Sec6l-mediated Transfer, Protein Secretion, Biochemistry +10

Association of class I major histocompatibility heavy and light chains induced by viral peptides

Alain Townsend, Claes Öhlén, Judy Bastin et al. · Nature · 1989 · 987 citations

Histocompatibility, Pathogenesis, Immunology +11

Empty MHC class I molecules come out in the cold

Hans-Gustaf Ljunggren, Nico J. Stam, Claes Öhlén et al. · Nature · 1990 · 932 citations

Engineering, Physics, Empty Mhc Class +6