Concepedia

Classical Mhc Molecules

Classical MHC Molecules is a class of highly polymorphic cell surface glycoproteins responsible for presenting peptide antigens to T cells, distinguished from non-classical MHC molecules by their central role in adaptive immunity and extensive genetic diversity.

362

Publications

23.5K

Citations

1.7K

Authors

562

Institutions

Publications per year

2017–2026

38

Variants

Classical Major Histocompatibility Complex MoleculesClassical Mhc

Parents

Publications

362

Surface Expression of HLA-E, an Inhibitor of Natural Killer Cells, Enhanced by Human Cytomegalovirus gpUL40

Peter Tomašec, Véronique M. Braud, Carole Rickards et al. · Science · 2000 · 664 citations

, , +17

Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

Mitsunori Shiroishi, Kouhei Tsumoto, K. Amano et al. · Proceedings of the National Academy of Sciences · 2003 · 548 citations · Full text

, , +16

Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition

Branca Pereira, Oliver Devine, Milica Vukmanovic‐Stejic et al. · Nature Communications · 2019 · 533 citations · Full text

, , +16

Assembly of MHC class I molecules analyzed in vitro

Alain Townsend, Tim Elliott, Vincenzo Cerundolo et al. · Cell · 1990 · 487 citations

, , +11

IL-10 selectively induces HLA-G expression in human trophoblasts and monocytes

Philippe Moreau, Francisco Adrian-Cabestre, Catherine Menier et al. · International Immunology · 1999 · 405 citations · Full text

, , +17

1–5 of 362

Authors

1.7K

  1. JM
    Johannes M. Dijkstra

    Fujita Health University, Japan

    9 publications · 537 citations

    9

    h-index

  2. IS
    Iwona Stroynowski

    The University of Texas Southwestern Medical Center, United States

    8 publications · 425 citations

    8

    h-index

  3. JK
    Jim Kaufman

    University of Cambridge, United Kingdom

    8 publications · 596 citations

    8

    h-index

  4. GW
    Geoffrey W. Butcher

    Babraham Institute, United Kingdom

    8 publications · 312 citations

    8

    h-index

  5. MS
    Margarita Salcedo

    Karolinska Institutet, Sweden

    6 publications · 210 citations

    6

    h-index

1–5 of 1.7K

Institutions

562

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    15 h-index

    48 publications

    5.3K citations

  2. Harvard University

    Cambridge, United States

    14 h-index

    54 publications

    8.2K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    12 h-index

    32 publications

    4.1K citations

  4. Stanford University

    Stanford, United States

    12 h-index

    46 publications

    3.8K citations

  5. Babraham Institute

    Cambridge, United Kingdom

    11 h-index

    38 publications

    1.9K citations

  6. Institut Pasteur

    Paris, France

    10 h-index

    28 publications

    2K citations

  7. The University of Texas Southwestern Medical Center

    Dallas, United States

    10 h-index

    21 publications

    1.7K citations

  8. Inserm

    Paris, France

    10 h-index

    24 publications

    1.3K citations

1–8 of 562

Venues

  1. The Journal of Immunology

    JI · 81 publications · 4.4K citations

    41

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 28 publications · 3.5K citations

    26

    h-index

  3. Immunogenetics

    31 publications · 1.3K citations

    23

    h-index

  4. European Journal of Immunology

    EJI · 24 publications · 1.3K citations

    20

    h-index

  5. PubMed

    Repository · 13 publications · 714 citations

    13

    h-index

1–5