Concepedia

4-Amino-2-cyanopyrimidines: Novel scaffold for nonpeptidic cathepsin S inhibitors

Osamu Irie, Fumiaki Yokokawa, Takeru Ehara, Atsuko Iwasaki, Yuki Iwaki, Yuko Hitomi, Kazuhide Konishi, Masashi Kishida, Atsushi Toyao, Keiichi Masuya,

Bioorganic & Medicinal Chemistry Letters · 2008 · 17 citations · 15 references

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15

Essential Role for Cathepsin S in MHC Class II–Associated Invariant Chain Processing and Peptide Loading

Richard J. Riese, Paula Wolf, Dieter Brömme et al. · Immunity · 1996 · 529 citations · Full text

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Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain

Anna K. Clark, Ping K. Yip, John Grist et al. · Proceedings of the National Academy of Sciences · 2007 · 481 citations · Full text

, , +17

Design of an Organocatalyst for the Enantioselective Diels−Alder Reaction with α-Acyloxyacroleins

Kazuaki Ishihara, Kazuhiko Nakano · Journal of the American Chemical Society · 2005 · 219 citations

, , +13

Role of the cysteine protease cathepsin S in neuropathic hyperalgesia

J. Elaine Barclay, Anna K. Clark, Pam Ganju et al. · Pain · 2007 · 133 citations

, , +17

Specificity Determinants of Human Cathepsin S Revealed by Crystal Structures of Complexes<sup>,</sup>

Thomas Pauly, Traian Sulea, Mark Ammirati et al. · Biochemistry · 2003 · 87 citations

, , +17