Fumiaki Yokokawa

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling

Siew Pheng Lim, Christian G. Noble, Cheah C. Seh et al. · PLoS Pathogens · 2016 · 174 citations · Full text

Viral Replication, Molecular Biology, Antiviral Drug +18

Structure, Synthesis, and Biological Properties of Kalkitoxin, a Novel Neurotoxin from the Marine Cyanobacterium <i>Lyngbya </i><i>m</i><i>ajuscula</i>

Min Wu, Tatsufumi Okino, Lisa Nogle et al. · Journal of the American Chemical Society · 2000 · 131 citations

Microbial Toxin, Molecular Pharmacology, Toxinology +13

Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels

W. I. Li, Frederick W. Berman, Tatsufumi Okino et al. · Proceedings of the National Academy of Sciences · 2001 · 103 citations · Full text

Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design

Fumiaki Yokokawa, Shahul Nilar, Christian G. Noble et al. · Journal of Medicinal Chemistry · 2016 · 97 citations

Medicinal Chemistry, Natural Sciences, Medicine +14

A Targeted Library of Small-Molecule, Tyrosine, and Dual-Specificity Phosphatase Inhibitors Derived from a Rational Core Design and Random Side Chain Variation

Robert Rice, James M. Rusnak, Fumiaki Yokokawa et al. · Biochemistry · 1997 · 84 citations