Concepedia

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

Marius Dannappel, Katerina Vlantis, Snehlata Kumari, Apostolos Polykratis, Chun Kim, Laurens Wachsmuth, Christina Eftychi, Juan Lin, Teresa Corona, Nicole Hermance,

Nature · 2014 · 550 citations · 41 references

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41

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

, , +14

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Taro Kawai, Ken Takahashi, Shintaro Sato et al. · Nature Immunology · 2005 · 2.5K citations

, , +12

IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Florian R. Greten, Lars Eckmann, Tim F. Greten et al. · Cell · 2004 · 2.4K citations · Full text

, , +16

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda et al. · Immunity · 1998 · 2K citations · Full text

, , +14

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

Yanfang Fu, Jeffry D. Sander, Deepak Reyon et al. · Nature Biotechnology · 2014 · 2K citations · Full text

, , +14