Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

Boris Strilić, Lida Yang, Julián Albarrán-Juárez, +5

Nature

Endothelial Cell PathobiologyCancer ResearchAngiogenesisMedicineApoptosis +11

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

Marius Dannappel, Katerina Vlantis, Snehlata Kumari, +13

Nature

Signaling PathwayEpithelial HomeostasisReceptor Tyrosine KinaseApoptosisAutophagy +5

Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation

Huipeng Jiao, Laurens Wachsmuth, Snehlata Kumari, +9

Nature

InflammationTriggers Zbp1-dependent NecroptosisApoptosisImmunologyCell Death +5

RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

Juan Lin, Snehlata Kumari, Chun Kim, +4

Nature

InflammationCytokineApoptosisImmunologyChronic Inflammation +5

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

Najoua Lalaoui, Steven E. Boyden, Hirotsugu Oda, +51

Nature

Autoinflammatory DisordersPathogenesisImmunologyApoptosisCell Death +7

FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

Robin Schwarzer, Huipeng Jiao, Laurens Wachsmuth, +2

Immunity

InflammationChronic Inflammatory DiseasesAutoimmune DiseaseMucosal ImmunologyMedicine +13

ADAR1 averts fatal type I interferon induction by ZBP1

Huipeng Jiao, Laurens Wachsmuth, Simone Wolf, +14

Nature

Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment

Christina Eftychi, Robin Schwarzer, Katerina Vlantis, +7

Immunity

InflammationChronic Inflammatory DiseasesAllergyMucosal ImmunologyIntestinal Barrier Impairment +9

Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay

Kusum Singh, Laurens Wachsmuth, Andreas E. Kulozik, +1

RNA Biology

Nonsense-mediated DecayGeneticsRna SplicingGenomic MechanismMolecular Biology +16

Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition

Jessica Gräb, Isabelle Suárez, Edeltraud van Gumpel, +12

Nature Communications