Concepedia

Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors

Bin Wu, Huiling Wang, Victor J. Cee, Brian A. Lanman, Thomas Nixey, Liping H. Pettus, Anthony B. Reed, Ryan P. Wurz, Nadia Guerrero, Christine Sastri,

Bioorganic & Medicinal Chemistry Letters · 2015 · 32 citations · 27 references

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27

Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

H. T. M. Cuypers, Gerard C.M. Selten, Wim Quint et al. · Cell · 1984 · 645 citations

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The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor

Casey Fox, Peter S. Hammerman, Ryan M. Cinalli et al. · Genes & Development · 2003 · 331 citations · Full text

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Pim‐1 kinase promotes inactivation of the pro‐apoptotic Bad protein by phosphorylating it on the Ser<sup>112</sup> gatekeeper site

Teija L. T. Aho, Jouko Sandholm, Katriina Peltola et al. · FEBS Letters · 2004 · 320 citations

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Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase

Kevin Qian, Lian Wang, Eugene R. Hickey et al. · Journal of Biological Chemistry · 2004 · 288 citations · Full text

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The PIM-2 Kinase Phosphorylates BAD on Serine 112 and Reverses BAD-induced Cell Death

Bin Yan, Marina Zemskova, Sheldon L. Holder et al. · Journal of Biological Chemistry · 2003 · 259 citations · Full text

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