Thomas Nixey - Concepedia

Author

Thomas Nixey

Amgen (United States)

Also Known As

T. E. NIXEY, Thomas E. Nixey, Thomas Nixey

Publications

977

Citations

H-Index

Concepts

All Affiliations

Amgen (United States)

About

Thomas Nixey is an author at Amgen (United States) specializing in drug discovery, natural sciences, and organic chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	256
2	Natural Sciences	7	7	250
3	Biochemistry	6	6	231
4	Engineering	5	5	217
5	Biomolecular Engineering	3	3	134

Thomas Nixey

Publications

948

Citations

H-Index

Page 1

	Year	Citations
From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Yuan Cheng, Ted Judd, Michael D. Bartberger, Journal of Medicinal Chemistry	2011	136
Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline Adrian L. Smith, Frenel DeMorin, Nick A. Paras, Journal of Medicinal Chemistry Aminoisoquinoline CoreSelective InhibitorsPharmacotherapyMutant B-raf PathwayPharmaceutical Chemistry	2009	103
Novel Vanilloid Receptor-1 Antagonists: 2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate Elizabeth M. Doherty, Christopher Fotsch, Anthony W. Bannon, Journal of Medicinal Chemistry	2007	98
Fragment Based Drug Discovery: Practical Implementation Based on <sup>19</sup>F NMR Spectroscopy John B. Jordan, Leszek Poppe, Xiaoyang Xia, Journal of Medicinal Chemistry	2011	81
The one-pot solution phase preparation of fused tetrazole-ketopiperazines Thomas Nixey, Michael Kelly, Christopher Hulme Tetrahedron Letters Organic ChemistryFused Tetrazole-ketopiperazinesSynthesis MethodChemistry	2000	76
Short solution phase preparation of fused azepine-tetrazoles via a UDC (Ugi/de-Boc/cyclize) strategy Thomas Nixey, Michael Kelly, David Semin, Tetrahedron Letters Materials ScienceEngineeringOrganic ChemistryCatalysisChemistry	2002	64
Two-step solution-phase synthesis of novel quinoxalinones utilizing a UDC (Ugi/de-Boc/cyclize) strategy Thomas Nixey, Paul Tempest, Christopher Hulme Tetrahedron Letters EngineeringTwo-step Solution-phase SynthesisOrganic ChemistryNovel QuinoxalinonesChemistry	2002	63
Rapid generation of cis-constrained norstatine analogs using a TMSN3-modified Passerini MCC/N-capping strategy Thomas Nixey, Christopher Hulme Tetrahedron Letters EngineeringBioelectronicsCis-constrained Norstatine AnalogsRapid GenerationChemistry	2002	52
Novel Vanilloid Receptor-1 Antagonists: 1. Conformationally Restricted Analogues of<i>trans</i>-Cinnamides Mark H. Norman, Jiawang Zhu, Christopher Fotsch, Journal of Medicinal Chemistry Pain MedicineTransient Receptor PotentialMolecular PainPharmacotherapyMolecular Pharmacology	2007	42
Library Generation via Postcondensation Modifications of Isocyanide-Based Multicomponent Reactions Christopher Hulme, Hugues Bienaymé, Thomas Nixey, Methods in enzymology on CD-ROM/Methods in enzymology Combinatorial ChemistryLibrary GenerationOrganic ChemistryChemistrySynthetic Chemistry	2003	40

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