Anthony B. Reed

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 722 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold

Brad Herberich, Guoqiang Cao, Partha Chakrabarti et al. · Journal of Medicinal Chemistry · 2008 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511

Mark H. Norman, Kristin L. Andrews, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2012 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Structure-Based Design of a Novel Series of Potent, Selective Inhibitors of the Class I Phosphatidylinositol 3-Kinases

Adrian L. Smith, Noel D. D’Angelo, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2012 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors

Liping H. Pettus, Kristin L. Andrews, Shon K. Booker et al. · Journal of Medicinal Chemistry · 2016 · 41 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8