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First generation 5-vinyl-3-pyridinecarbonitrile PKCθ inhibitors

Chuansheng Niu, Diane H. Boschelli, L. Nathan Tumey, Niala Bhagirath, Joan Subrath, Jaechul Shim, Yan Wang, Biqi Wu, Clark N. Eid, Julie Lee,

Bioorganic & Medicinal Chemistry Letters · 2009 · 23 citations · 19 references

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19

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cδ

Akitomo Miyamoto, Keiko Nakayama, Keiichi I. Nakayama et al. · Nature · 2002 · 419 citations

, , +11

The reaction of vinyl grignard reagents with 2-substituted nitroarenes: A new approach to the synthesis of 7-substituted indoles

Giuseppe Bartoli, Gianni Palmieri, Marcella Bosco et al. · Tetrahedron Letters · 1989 · 327 citations

, , +9

Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells.

Gottfried Baier, David Telford, Leslie Giampa et al. · Journal of Biological Chemistry · 1993 · 305 citations · Full text

, , +8

Protein kinase Cδ controls self-antigen-induced B-cell tolerance

Ingrid Mecklenbräuker, Kaoru Saijo, Nai‐Ying Zheng et al. · Nature · 2002 · 268 citations

, , +12

Protein Kinase C θ Is Critical for the Development of In Vivo T Helper (Th)2 Cell But Not Th1 Cell Responses

Benjamin J. Marsland, Timothy Soos, Gérald F. Späth et al. · The Journal of Experimental Medicine · 2004 · 203 citations · Full text

, , +17