Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

Jens Wrammert, Kenneth G. C. Smith, Joe Miller, +12

Nature

MedicineImmunologyVirologyAntibody EngineeringAntibody Screening +2

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

Jens Wrammert, Dimitrios Koutsonanos, Guimei Li, +27

The Journal of Experimental Medicine

VaccinationPandemic H1n1Vaccine DevelopmentNeutralizing AntibodiesVaccine Target +9

Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans

Thomas Hagan, Mario Cortese, Nadine Rouphael, +26

Cell

ProbioticDysbiosisMucosal ImmunologyAntibioticsGut Microbiology +8

Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

Kenneth Smith, Lori Garman, Jens Wrammert, +4

Nature Protocols

VaccinationVaccinologyMedicineVaccine TargetImmunology +10

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

Guimei Li, Christopher Chiu, Jens Wrammert, +13

Proceedings of the National Academy of Sciences

VaccinationCross-protectionAllergyNeutralizing AntibodiesConserved Stem Region +10

p38 Kinase Is Activated in the Alzheimer's Disease Brain

Kenneth Hensley, Robert A. Floyd, Nai‐Ying Zheng, +10

Journal of Neurochemistry

Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection

Carole J. Henry Dunand, Paul E. Leon, Min Huang, +16

Cell Host & Microbe

VaccinologyVaccinationCross-protectionVaccine DevelopmentVaccine Target +7

Protein kinase Cδ controls self-antigen-induced B-cell tolerance

Ingrid Mecklenbräuker, Kaoru Saijo, Nai‐Ying Zheng, +2

Nature

Adaptive Immune SystemMedicineImmunologyImmunologic MechanismAutoimmunity +5

Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013–2014 influenza season

Susanne L. Linderman, Benjamin S. Chambers, Seth J. Zost, +18

Proceedings of the National Academy of Sciences

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors

J. Andrew Duty, Péter Szodoray, Nai‐Ying Zheng, +10

The Journal of Experimental Medicine