Concepedia

The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II

Brian B. Hasinoff, Xing Wu, John L. Nitiss, Ragu Kanagasabai, Jack C. Yalowich

Biochemical Pharmacology · 2012 · 55 citations · 34 references

DOI

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References

34

Improved protein–ligand docking using GOLD

Marcel L. Verdonk, Jason C. Cole, Michael J. Hartshorn et al. · Proteins Structure Function and Bioinformatics · 2003 · 3K citations · Full text

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Comprehensive analysis of kinase inhibitor selectivity

Mindy I. Davis, Jeremy P. Hunt, Sanna Herrgård et al. · Nature Biotechnology · 2011 · 2.4K citations · Full text

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Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

K M Tewey, Thomas C. Rowe, Liu Yang et al. · Science · 1984 · 1.5K citations

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Structures of Three Classes of Anticancer Agents Bound to the Human Topoisomerase I−DNA Covalent Complex

Bart L. Staker, M.D. Feese, Mark Cushman et al. · Journal of Medicinal Chemistry · 2005 · 535 citations · Full text

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Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide

Chyuan-Chuan Wu, Tsai‐Kun Li, Lynn Farh et al. · Science · 2011 · 514 citations

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