Jeremy P. Hunt

A quantitative analysis of kinase inhibitor selectivity

Mazen W. Karaman, Sanna Herrgård, Daniel K. Treiber et al. · Nature Biotechnology · 2008 · 2.4K citations

Drug Target, Signal Transduction, Medicine +6

Comprehensive analysis of kinase inhibitor selectivity

Mindy I. Davis, Jeremy P. Hunt, Sanna Herrgård et al. · Nature Biotechnology · 2011 · 2.3K citations · Full text

Drug Target, Signal Transduction, Medicine +5

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia

Catherine C. Smith, Qi Wang, Chen-Shan Chin et al. · Nature · 2012 · 734 citations

Hematological Malignancy, Medicine, Mixed-phenotype Acute Leukemia +10

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

Pietro Ciceri, Susanne Müller, Alison O’Mahony et al. · Nature Chemical Biology · 2014 · 347 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +6

Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia

Yoshihiro Gocho, Jingjing Liu, Jianzhong Hu et al. · Nature Cancer · 2021 · 148 citations · Full text

Systems Pharmacology, Hematological Malignancy, Medicine +11