Concepedia

John L. Nitiss

JL

Statistics

Publications

75

Citations

4.3K

H-Index

39

Active since

1984

Affiliations

St. Jude Children's Research Hospital(Current)

University of Illinois Chicago, Rockford campus

Children's Hospital of Los Angeles

Illinois College

John L. Nitiss is an author at St. Jude Children's Research Hospital specializing in topoisomerase activity, molecular biology, and life sciences.

Publications per year

1984–2023

75

Publications

75

DNA topoisomerase-targeting antitumor drugs can be studied in yeast.

John L. Nitiss, J C Wang · Proceedings of the National Academy of Sciences · 1988 · 498 citations · Full text

Medicine, Oncology, Pharmacology +17

Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage

Karin C. Nitiss, Mobeen Malik, Xiaoping He et al. · Proceedings of the National Academy of Sciences · 2006 · 157 citations · Full text

Medicine, Molecular Biology, Oncology +17

Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes

Sachin Katyal, Youngsoo Lee, Karin C. Nitiss et al. · Nature Neuroscience · 2014 · 146 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA.

John L. Nitiss, James C. Wang · Molecular Pharmacology · 1996 · 145 citations

Life Sciences, Cell Biology, Pharmacology +17

A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation

Yilun Sun, Lisa M. Jenkins, Yijun Su et al. · Science Advances · 2020 · 142 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

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