J C Wang

DNA topoisomerase-targeting antitumor drugs can be studied in yeast.

John L. Nitiss, J C Wang · Proceedings of the National Academy of Sciences · 1988 · 498 citations · Full text

Medicine, Oncology, Pharmacology +17

Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22.

M Tsai-Pflugfelder, Leroy F. Liu, A A Liu et al. · Proceedings of the National Academy of Sciences · 1988 · 397 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

DNA topoisomerases: why so many?

J C Wang · Journal of Biological Chemistry · 1991 · 366 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Antitumor bisdioxopiperazines inhibit yeast DNAtopoisomerase II by trapping the enzyme in the form of a closed proteinclamp.

Joaquím Roca, Ryoji Ishida, James M. Berger et al. · Proceedings of the National Academy of Sciences · 1994 · 354 citations · Full text

Medicine, Molecular Biology, Pharmacology +12

Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes.

Henggui Zhang, J C Wang, Leroy F. Liu · Proceedings of the National Academy of Sciences · 1988 · 284 citations · Full text

Life Sciences, Biochemistry, Genetics +15