Joaquím Roca

Antitumor bisdioxopiperazines inhibit yeast DNAtopoisomerase II by trapping the enzyme in the form of a closed proteinclamp.

Joaquím Roca, Ryoji Ishida, James M. Berger et al. · Proceedings of the National Academy of Sciences · 1994 · 351 citations · Full text

Molecular Biology, Antimicrobial Chemotherapy, Type Ii Dna +18

The capture of a DNA double helix by an ATP-dependent protein clamp: A key step in DNA transport by type II DNA topoisomerases

Joaquím Roca, James C. Wang · Cell · 1992 · 310 citations

Chromatin, Atp-dependent Protein Clamp, Dna +9

DNA transport by a type II DNA topoisomerase: Evidence in favor of a two-gate mechanism

Joaquím Roca, James C. Wang · Cell · 1994 · 289 citations

Chromatin, Natural Sciences, Dna Analysis +8

Storage conditions of intestinal microbiota matter in metagenomic analysis

Silvia T. Cardona, Anat Eck, Montserrat Cassellas et al. · BMC Microbiology · 2012 · 270 citations · Full text

Knotting probability of DNA molecules confined in restricted volumes: DNA knotting in phage capsids

Javier Arsuaga, Mariel Vázquez, Sònia Trigueros et al. · Proceedings of the National Academy of Sciences · 2002 · 258 citations · Full text

Molecular Biology, Molecular Genetics, Restricted Volumes +17