Concepedia

Karin C. Nitiss

KC

Statistics

Publications

28

Citations

1.3K

H-Index

19

Active since

2000

Affiliations

St. Jude Children's Research Hospital(Current)

University of Illinois Chicago, Rockford campus

Illinois College

University of Illinois Urbana-Champaign

Center for Cancer Research

Karin C. Nitiss is an author at St. Jude Children's Research Hospital specializing in medicine, molecular biology, and natural sciences.

Top concepts

MedicineMolecular BiologyNatural SciencesChromatinDna ReplicationCell BiologyGenome InstabilityGeneticsPathologyProteomics

Publications per year

2000–2023

28

Publications

28

Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage

Karin C. Nitiss, Mobeen Malik, Xiaoping He et al. · Proceedings of the National Academy of Sciences · 2006 · 156 citations · Full text

Chromatin, Genome Instability, Tdp1 Gene +15

Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes

Sachin Katyal, Youngsoo Lee, Karin C. Nitiss et al. · Nature Neuroscience · 2014 · 145 citations · Full text

Chromatin, Genome Instability, Neurodegenerative Diseases +10

A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation

Yilun Sun, Lisa M. Jenkins, Yijun Su et al. · Science Advances · 2020 · 133 citations · Full text

Reductive Stress, Chromatin, Genome Instability +15

Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2·DNA and Top2·RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)

Rui Gao, Matthew J. Schellenberg, Shar-yin N. Huang et al. · Journal of Biological Chemistry · 2014 · 117 citations · Full text

A Novel Mechanism of Cell Killing by Anti-topoisomerase II Bisdioxopiperazines

Lars H. Jensen, Karin C. Nitiss, Angela Rose et al. · Journal of Biological Chemistry · 2000 · 96 citations · Full text

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