An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting, +1

Nature

ThrombopoiesisThrombosisBiochemistryCardiovascular DiseaseMedicine +10

The importance of phospholipase-A2 in prostaglandin biosynthesis

Roderick J. Flower, Geoffrey J. Blackwell

Biochemical Pharmacology

BiosynthesisBiochemistryNatural SciencesCellular BiochemistryProstaglandin Biosynthesis +2

Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme.

Martin E. Hemler, William E.M. Lands

Journal of Biological Chemistry

Aldo-keto ReductaseIron MetabolismStannous ChlorideMolecular BiologyIron Content +14

Phospholipid precursors of prostaglandins

William E.M. Lands, Bengt Samuelsson

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

BiosynthesisBiochemistryGlycobiologyLipid ChemistryLipid Synthesis +1

Stimulation and Blockade of Prostaglandin Biosynthesis

William L. Smith, William E.M. Lands

Journal of Biological Chemistry

Sheep Vesicular GlandLipid PeroxidationSecondary MetaboliteGastrointestinal Peptide HormoneOxidative Stress +15

Selective inhibition by mepacrine of the release of “rabbit aorta contracting substance” evoked by the administration of bradykinin

B. Boris Vargaftig, N. Dao Hai

Journal of Pharmacy and Pharmacology

Cardiovascular PharmacologyPharmacotherapyCardiovascular Function“ RabbitExperimental Pharmacology +18

Hormone selective lipase activation in the isolated rabbit heart

Wei Hsueh, Peter C. Isakson, Philip Needleman

Prostaglandins

Animal PhysiologyBiochemistryPhysiologyVascular BiologyLipoprotein Metabolism +5

Properties of a novel preparation of prostaglandin synthetase from sheep seminal vesicles

Donald P. Wallach, Edward G. Daniels

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Animal ReproductionBiosynthesisFertilityBiochemistryNatural Sciences +9

Anoxia-induced release of prostaglandins in rabbit isolated hearts.

A. Jay Block, Harold Feinberg, K Herbaczyńska-Cedro, +1

Circulation Research

Evoked Prostaglandin ReleaseMedicineVascular PharmacologyPhysiologyProstaglandin Release +11

Relationship between oxygen tension, coronary vasodilation and prostaglandin biosynthesis in the isolated rabbit heart

Philip Needleman, Sharon Key, Peter C. Isakson, +1

Prostaglandins

MedicinePhysiologyCoronary VasodilationVascular BiologyTissue Oxygenation +8