Ryszard J. Gryglewski

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

Ryszard J. Gryglewski, Richard Palmer, Salvador Moncada · Nature · 1986 · 2.4K citations

Life Sciences, Cell Biology, Physiology +13

Flavonoids are scavengers of superoxide anions

Jadwiga Robak, Ryszard J. Gryglewski · Biochemical Pharmacology · 1988 · 1.6K citations

Life Sciences, Biochemistry, Chemistry +11

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

Ryszard J. Gryglewski, Stuart Bunting, Salvador Moncada et al. · Prostaglandins · 1976 · 1K citations

Medicine, Cardiology, Hematology +13

A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, Stuart Bunting et al. · Prostaglandins · 1976 · 605 citations

Life Sciences, Biochemistry, Physiology +16