An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting, +1

Nature

ThrombopoiesisThrombosisBiochemistryCardiovascular DiseaseMedicine +10

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model.

S Takeshita, Long Zheng, Edi Brogi, +6

Journal of Clinical Investigation

HypertensionBiomedical EngineeringSevere Limb IschemiaSingle Intraarterial BolusRegenerative Medicine +17

Modulation of human platelet adenylate cyclase by prostacyclin (PGX)

Robert R. Gorman, S Bunting, O.V. Miller

Prostaglandins

ThrombopoiesisThrombosisMolecular PharmacologyBlood PlateletMedicine +5

Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.

John E. Bleasdale, Nirja Thakur, R S Gremban, +4

Journal of Pharmacology and Experimental Therapeutics

Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides

Philip Needleman, Salvador Moncada, S Bunting, +3

Nature

ThrombopoiesisThrombosisBiochemistryBlood PlateletPlatelet Microsomes +10

Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors.

Mark S. Dennis, William J. Henzel, Robert Pitti, +5

Proceedings of the National Academy of Sciences

ImmunologyPharmacotherapyChemical BiologyPlatelet AggregationMolecular Pharmacology +17

Physiological assessment of augmented vascularity induced by VEGF in ischemic rabbit hindlimb

Christophe Bauters, Takayuki Asahara, Liangliang Zheng, +5

American Journal of Physiology-Heart and Circulatory Physiology

Responses of human and baboon arteries to prostaglandin endoperoxides and biologically generated and synthetic prostacyclin: their relevance to cerebral arterial spasm in man.

D J Boullin, S Bunting, WP Blaso, +2

British Journal of Clinical Pharmacology

Vascular DiseaseIsolated StripsCerebral Arterial SpasmIsolated Organ BathCerebral Vascular Regulation +23

Metabolism of leukotriene A4 by human erythrocytes. A novel cellular source of leukotriene B4.

Fidelma Fitzpatrick, W. F. LIGGETT, J McGee, +3

Journal of Biological Chemistry

Inhibition of phospholipase C dependent processes by U-73, 122.

Bleasdale Je, Bundy Gl, S Bunting, +4

PubMed

Molecular PharmacologyProtein FunctionSignal TransductionBiochemistryMedicine +6