Concepedia

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

Xiang‐Ping Yang, Kamran Ghoreschi, Scott Steward-Tharp, Jaime Rodriguez‐Canales, Jinfang Zhu, John R. Grainger, Kiyoshi Hirahara, Hong‐Wei Sun, Lai Wei, Golnaz Vahedi,

Nature Immunology · 2011 · 576 citations · 44 references

DOIFull text

Open access

Concepts

References

44

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

, , +17

Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology · 2005 · 4.7K citations

, , +17

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Marc Veldhoen, Richard J. Hocking, Christopher J. Atkins et al. · Immunity · 2006 · 3.6K citations · Full text

, , +12

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

Nathaniel D. Heintzman, Rhona Stuart, Gary C. Hon et al. · Nature Genetics · 2007 · 3.5K citations

, , +16

Reciprocal T <sub>H</sub> 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid

Daniel Mucida, Yunji Park, Gisen Kim et al. · Science · 2007 · 1.9K citations

, , +16