Concepedia

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

Morgan L. Maeder, James Angstman, Marcy E. Richardson, Samantha J Linder, Vincent Cascio, Shengdar Q. Tsai, Quan Van Ho, Jeffry D. Sander, Deepak Reyon, B Bernstein,

Nature Biotechnology · 2013 · 506 citations · 25 references

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25

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Mamta Tahiliani, Kian Peng Koh, Yinghua Shen et al. · Science · 2009 · 5.8K citations · Full text

, , +17

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

Shinsuke Ito, Li Shen, Qing Dai et al. · Science · 2011 · 3.4K citations

, , +5

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

Yufei He, Bin-Zhong Li, Zheng Li et al. · Science · 2011 · 2.8K citations

, , +12

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

Shinsuke Ito, Ana C. D’Alessio, Olena Taranova et al. · Nature · 2010 · 2.5K citations

, , +8

A TALE nuclease architecture for efficient genome editing

Jeffrey C. Miller, Siyuan Tan, Guijuan Qiao et al. · Nature Biotechnology · 2010 · 2.1K citations

, , +14