Transgene Targeting is a site-specific recombination method that enables the precise integration of exogenous genetic sequences into predetermined genomic loci through the action of recombinase enzymes recognizing specific DNA target sites.
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56
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Publications
452
Inducible Gene Targeting in Mice
Ralf Kühn, Frieder Schwenk, Michel Aguet et al. · Science · 1995 · 1.9K citations · Full text
Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting
Hua Gu, Jamey D. Marth, Paul C. Orban et al. · Science · 1994 · 1.4K citations
Cre recombinase: The universal reagent for genome tailoring
András Nagy · genesis · 2000 · 1.2K citations
1–5 of 452
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624
Harvard University
Cambridge, United States
21 h-index
86 publications
15K citations
Howard Hughes Medical Institute
Chevy Chase, United States
21 h-index
66 publications
15.7K citations
Centre National de la Recherche Scientifique
Paris, France
11 h-index
44 publications
4.9K citations
National Institutes of Health
Bethesda, United States
11 h-index
38 publications
19.5K citations
University of California, San Francisco
San Francisco, United States
10 h-index
19 publications
2.1K citations
Baylor College of Medicine
Houston, United States
10 h-index
38 publications
3.7K citations
Inserm
Paris, France
9 h-index
36 publications
3.8K citations
University of Cologne
Cologne, Germany
8 h-index
23 publications
11.5K citations
1–8 of 624
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- Nucleic Acids Research
38 publications · 3.4K citations
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- genesis
26 publications · 3.7K citations
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- Proceedings of the National Academy of Sciences
PNAS · 20 publications · 5.1K citations
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- PLoS ONE
18 publications · 1.2K citations
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- Transgenic Research
11 publications · 850 citations
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