Concepedia

Modulation of Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) Transport Activities by Endogenous and Exogenous Glutathione-Conjugated Catechol Metabolites

Andrew J. Slot, Dana D Wise, Roger G. Deeley, Terrence J. Monks, Susan P.C. Cole

Drug Metabolism and Disposition · 2007 · 36 citations · 31 references

DOI

Concepts

References

31

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

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Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells

Yunhai Cui, Jörg König, Ulrike Buchholz et al. · Molecular Pharmacology · 1999 · 681 citations

, , +14

Multidrug Resistance Protein (MRP)-mediated Transport of Leukotriene C4 and Chemotherapeutic Agents in Membrane Vesicles

Douglas W. Loe, Kurt C. Almquist, Roger G. Deeley et al. · Journal of Biological Chemistry · 1996 · 560 citations · Full text

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Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics

Giuseppe Galati · Toxicology · 2002 · 524 citations

, , +16

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

Jan Wijnholds, Raymond Evers, Manuel R. van Leusden et al. · Nature Medicine · 1997 · 438 citations

, , +14