Manuel R. van Leusden

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

G J Zaman, M J Flens, Manuel R. van Leusden et al. · Proceedings of the National Academy of Sciences · 1994 · 690 citations · Full text

Molecular Pharmacology, Protein Mrp, Drug Resistance Analysis +15

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

Jan Wijnholds, Raymond Evers, Manuel R. van Leusden et al. · Nature Medicine · 1997 · 437 citations

Inflammation, Anti-inflammatory, Medicine +9

Hemidesmosome Formation Is Initiated by the β4 Integrin Subunit, Requires Complex Formation of β4 and HD1/Plectin, and Involves a Direct Interaction between β4 and the Bullous Pemphigoid Antigen 180

Roel Q.J. Schaapveld, Luca Borradori, Dirk Geerts et al. · The Journal of Cell Biology · 1998 · 183 citations · Full text

The Localization of Bullous Pemphigoid Antigen 180 (BP180) in Hemidesmosomes Is Mediated by Its Cytoplasmic Domain and Seems to be Regulated by the β4 Integrin Subunit

Luca Borradori, Peter J. Koch, Carien M. Niessen et al. · The Journal of Cell Biology · 1997 · 124 citations · Full text

The Unique Cytoplasmic Domain of the Human Integrin Variant β4E Is Produced by Partial Retention of Intronic Sequences

Manuel R. van Leusden, Ingrid Kuikman, Arnoud Sonnenberg · Biochemical and Biophysical Research Communications · 1997 · 25 citations

Developmental Biology, Intronic Sequences, Unique Cytoplasmic Domain +10