The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

G J Zaman, M J Flens, Manuel R. van Leusden, +7

Proceedings of the National Academy of Sciences

Molecular PharmacologyProtein MrpDrug Resistance AnalysisProteinlipid InteractionBiochemistry +13

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

Michael Müller, Coby Meijer, G J Zaman, +5

Proceedings of the National Academy of Sciences

Drug Resistance AnalysisBiochemistryMedicineNatural SciencesLipid Peroxidation +11

Tissue distribution of the multidrug resistance protein.

M J Flens, G J Zaman, Paul van der Valk, +7

PubMed

Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines

G J Zaman, C. H. M. Versantvoort, Jasper Smit, +7

Lung Cancer

MedicineCancer BiologyAnti-cancer AgentProtein TransportPharmacology +4

Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies.

M J Flens, Miguel Izquierdo, George L. Scheffer, +4

PubMed

Immunocytochemical TechniqueImmunologyImmunoeditingPathologyImmunochemical Detection +18

Expression of the multidrug resistance-associated protein (MRP) gene in human cancers.

Kees Nooter, Anne Marie Westerman, M J Flens, +7

PubMed

Drug Resistance GenePathologyCancer BiologyTumor BiologyMrp Mrna +15

The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.

Roberto Tommasini, Raymond Evers, Esther Vogt, +5

Proceedings of the National Academy of Sciences

Molecular BiologyCellular PhysiologyDrug ResistanceBiochemical GeneticsYeast +14

Altered MRP is associated with multidrug resistance and reduced drug accumulation in human SW-1573 cells

EWHM Eijdems, G J Zaman, Marcel de Haas, +6

British Journal of Cancer

Molecular PharmacologyHuman Sw-1573 CellsDrug Resistance AnalysisMedicineReduced Drug Accumulation +7

Sequence of a cDNA encoding human ribosomal protein L26 and of a cDNA probably encoding human ribosomal protein L6

G J Zaman

Nucleic Acids Research

Natural SciencesGeneticsRna BiologyMolecular BiologyMolecular Genetics +3