Characterization and bioassay of post-translationally modified interferon α-2b expressed in Escherichia coli

Virus interference. I. The interferon

Alick Isaacs, J. Lindenmann · Proceedings of the Royal Society of London. Series B, Biological sciences · 1957 · 3.4K citations

Life Sciences, Immunology, Infectious Diseases +17

A general method for isolation of high molecular weight DNA from eukaryotes

Nikolaus Blin, Darrel W. Stafford · Nucleic Acids Research · 1976 · 2.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

The isolation of structural genes from libraries of eucaryotic DNA

Tom Maniatis, Ross C. Hardison, Elizabeth Lacy et al. · Cell · 1978 · 1.9K citations

Life Sciences, Genetics, Molecular Biology +11

Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid.

P H Hirel, M J Schmitter, P Dessen et al. · Proceedings of the National Academy of Sciences · 1989 · 765 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Human leukocyte interferon produced by E. coli is biologically active

David V. Goeddel, Elizabeth Yelverton, Axel Ullrich et al. · Nature · 1980 · 529 citations

Life Sciences, Immunology, Microbiology +8