Liver X receptor β activation induces pyroptosis of human and murine colon cancer cells

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

Faraaz B. Chekeni, Michael R. Elliott, Joanna K. Sandilos et al. · Nature · 2010 · 1.1K citations

Apoptosis, Cell Death, Cell Death Mechanisms +17

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Teresa Fernandes‐Alnemri, Jiang Wu, Je‐Wook Yu et al. · Cell Death and Differentiation · 2007 · 1K citations · Full text

Inflammation, Anti-inflammatory, Signal Transduction +11

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

Hasan Zaki, Kelli L. Boyd, Peter Vogel et al. · Immunity · 2010 · 958 citations · Full text

Inflammation, Inflammatory Disease, Mucosal Immunology +11

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

Irving C. Allen, Erin McElvania, Rita-Marie T. Woodford et al. · The Journal of Experimental Medicine · 2010 · 804 citations · Full text

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

Jeremy Dupaul-Chicoine, Garabet Yeretssian, Karine Doiron et al. · Immunity · 2010 · 505 citations · Full text

Inflammation, Intestinal Homeostasis, Medicine +10