Irving C. Allen

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

Irving C. Allen, Margaret A. Scull, Chris B. Moore et al. · Immunity · 2009 · 1.1K citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

Irving C. Allen, Erin McElvania, Rita-Marie T. Woodford et al. · The Journal of Experimental Medicine · 2010 · 819 citations · Full text

Medicine, Immunology, Pathobiology +17

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

Robin R. Craven, Xi Gao, Irving C. Allen et al. · PLoS ONE · 2009 · 434 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +17

NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

Irving C. Allen, Chris B. Moore, Monika Schneider et al. · Immunity · 2011 · 368 citations · Full text

Life Sciences, Immunology, Infectious Diseases +14

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

Stephen B. Willingham, Irving C. Allen, Dan T. Bergstralh et al. · The Journal of Immunology · 2009 · 349 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +17