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Engineered disulfide bonds increase active-site local stability and reduce catalytic activity of a cold-adapted alkaline phosphatase

EngineeringBiochemistryNatural SciencesBiocatalysisEnzyme CatalysisSynthetic BiologyEngineered Disulfide BondsActive-site Local StabilityCatalysisChemistryStructure-function Enzyme KineticsProtein PhosphorylationCold-adapted Alkaline Phosphatase