Concepedia

Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites

Satoshi Komoriya, Noriyasu Haginoya, Shozo Kobayashi, Tsutomu Nagata, Akiyoshi Mochizuki, Masanori Suzuki, Toshiharu Yoshino, Haruhiko Horino, Takayasu Nagahara, Makoto Suzuki,

Bioorganic & Medicinal Chemistry · 2005 · 30 citations · 28 references

DOI

Concepts

References

28

Interactive computer graphics: FRODO

Thomas A. Jones · Methods in enzymology on CD-ROM/Methods in enzymology · 1985 · 830 citations

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Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIa Investigators.

Circulation · 1994 · 498 citations

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Hirudin in acute myocardial infarction. Safety report from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A Trial.

Elliott M. Antman · Circulation · 1994 · 456 citations

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Structure of Human Des(1-45) Factor Xa at 2·2 Å Resolution

K. Padmanabhan, K. Padmanabhan, A. Tulinsky et al. · Journal of Molecular Biology · 1993 · 392 citations

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The Direct Thrombin Inhibitor Melagatran and Its Oral Prodrug H 376/95: Intestinal Absorption Properties, Biochemical and Pharmacodynamic Effects

David Gustafsson, Jan-Erik Nyström, Stefan Carlsson et al. · Thrombosis Research · 2001 · 302 citations

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