Akiyoshi Mochizuki

Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: Exploration of 6–6 fused rings as alternative S1 moieties

Kenji Yoshikawa, Shozo Kobayashi, Yumi Nakamoto et al. · Bioorganic & Medicinal Chemistry · 2009 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Design, synthesis, and biological activity of novel factor Xa inhibitors: Improving metabolic stability by S1 and S4 ligand modification

Satoshi Komoriya, Shozo Kobayashi, Ken Osanai et al. · Bioorganic & Medicinal Chemistry · 2005 · 42 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Design, synthesis, and biological activity of piperidine diamine derivatives as factor Xa inhibitor

Akiyoshi Mochizuki, Yumi Nakamoto, Hiroyuki Naito et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: Exploration of 5–6 fused rings as alternative S1 moieties

Kenji Yoshikawa, Aki Yokomizo, Hiroyuki Naito et al. · Bioorganic & Medicinal Chemistry · 2009 · 31 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites

Satoshi Komoriya, Noriyasu Haginoya, Shozo Kobayashi et al. · Bioorganic & Medicinal Chemistry · 2005 · 30 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17