Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes

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Reductive Stress, Mitophagy, Direct Inhibitor +11

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ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

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Signal Transduction, Signaling Pathway, Cell Regulation +11

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity

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Inflammation, Toll-like Receptors, Tlr4-mediated Innate Immunity +13

UVB Light Stimulates Production of Reactive Oxygen Species

Diane E. Heck, Anna M. Vetrano, Thomas M. Mariano et al. · Journal of Biological Chemistry · 2003 · 364 citations · Full text