Tumor Vessel Normalization by Chloroquine Independent of Autophagy

Hannelore Maes, Anna Kuchnio, Aleksandar Perić, +19

Cancer Cell

Cell AutophagyMitophagyAutophagyPathologyTumor Vessel Normalization +3

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy

Ali Talebi, Jonas Dehairs, Florian Rambow, +15

Nature Communications

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease

Wiebe Vanhove, Paul Peeters, Dominiek Staelens, +15

Inflammatory Bowel Diseases

BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton

H. Maes, Sofie Van Eygen, Dmitri V. Krysko, +6

Cell Death and Disease

Melanoma Cell MigrationImmunologyCell DeathCytoskeletonCancer Biology +20

Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes

An Van Laethem, Kris Nys, Sofie Van Kelst, +5

Free Radical Biology and Medicine

Reductive StressMedicinePhotocarcinogenesisApoptosisCell Death +8

The major secreted protein Msp1/p75 is O-glycosylated in Lactobacillus rhamnosus GG

Sarah Lebeer, Ingmar Claes, Crina I.A. Balog, +13

Microbial Cell Factories

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress

Eveline Hoefkens, Kris Nys, Jestinah Mahachie John, +8

Autophagy

A p38MAPK/HIF-1 Pathway Initiated by UVB Irradiation Is Required to Induce Noxa and Apoptosis of Human Keratinocytes

Kris Nys, An Van Laethem, Carine Michiels, +4

Journal of Investigative Dermatology

Uvb IrradiationApoptosisPhototoxicityCell DeathHuman Keratinocytes +7

Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease

Mohammad Salem, Ole Haagen Nielsen, Kris Nys, +2

Clinical and Translational Gastroenterology

Skin mild hypoxia enhances killing of UVB-damaged keratinocytes through reactive oxygen species-mediated apoptosis requiring Noxa and Bim

Kris Nys, Hannelore Maes, Graciela Andreï, +3

Free Radical Biology and Medicine

InflammationOphthalmologyCutaneous BiologyHypoxia (Medicine)Cell Death +7