Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

Kim Vriens, Stefan Christen, Sweta Parik, +43

Nature

Lineage PlasticityLipid SynthesisOmega-3 Fatty AcidMedicineCancer Cell Biology +6

The use of a glucose-reduced graphene oxide suspension for photothermal cancer therapy

Omid Akhavan, Elham Ghaderi, Samira Aghayee, +2

Journal of Materials Chemistry

NanotherapeuticsEngineeringBiomedical EngineeringGo SuspensionPolyethylene Glycol +18

CRISP-ID: decoding CRISPR mediated indels by Sanger sequencing

Jonas Dehairs, Ali Talebi, Yacine Chérifi, +1

Scientific Reports

Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism

Yanyan Cai, Jonathan Crowther, Tibor J. Pastor, +9

Cancer Cell

Tumor BiologyOncologyMedicineChromosome 8PDrug Response +8

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy

Ali Talebi, Jonas Dehairs, Florian Rambow, +15

Nature Communications

Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer

Kaylyn D. Tousignant, Anja Rockstroh, Berwyck L. J. Poad, +11

Cancer & Metabolism

Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

Maria I. Matias, Carmen S. Yong, Amir Foroushani, +24

Cell Reports

Inhibition of glutamine synthetase in monocytes from patients with acute-on-chronic liver failure resuscitates their antibacterial and inflammatory capacity

Hannelie Korf, Johannie du Plessis, Jos van Pelt, +18

Gut

Identification of drugs that restore primary cilium expression in cancer cells

Niamat Khan, Nicolas Willemarck, Ali Talebi, +11

Oncotarget

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers

Tom Van Nyen, Mélanie Planque, Lilian van Wagensveld, +22

Nature Communications