Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

Life Sciences, Genetics, Neurology +17

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel et al. · Proceedings of the National Academy of Sciences · 1993 · 4.3K citations · Full text

Life Sciences, Genetics, Neurology +17

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel et al. · Neurology · 1993 · 3.8K citations · Full text

Life Sciences, Genetics, Neurology +17

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

Warren J. Strittmatter, Karl H. Weisgraber, Daoyuan Huang et al. · Proceedings of the National Academy of Sciences · 1993 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +16

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

Yoshio Namba, Masanori Tomonaga, Hiroshi Kawasaki et al. · Brain Research · 1991 · 1.2K citations

Life Sciences, Neurology, Neuroscience +16